American Medical Association Studies Chinese
Medicine
In what has been hailed as a milestone on the road to the
creation of a single, integrated system of medicine, the American
Medical Association devoted its Nov. 11 1999 issue of JAMA
to research on alternative medicine. The issue featured three
randomized controlled trials of Chinese medical treatments,
making it the most heavily studied therapy in the journal.
The first study focused on the use of moxibustion for correction
of breech presentation in pregnancy. (Moxibustion is the burning
of a specific herbal preparation containing mugwort at an
acupuncture point.) Treatment was given from the 33rd week
of pregnancy through the 35th week. At the end of this period,
ultrasound showed that 98 of 130 fetuses (75.4%) in the moxibustion
group had turned to the normal head-down or cephalic position,
while only 62 out of 130 (47.7%) turned in the group which
didn’t have moxibustion. The authors concluded that
moxibustion is a safe effective therapy for this condition,
with additional advantage of being easy to administer at home,
with minimal training.
Another study examined the treatment of Irritable Bowel
Syndrome with Chinese herbal medicine. 116 patients were divided
into three groups: the first group received a standardized
Chinese herbal formula considered helpful in a broad range
of IBS patterns; the second group received an individualized
custom Chinese herbal formula; and the third group was given
a placebo in capsule form visually identical to the two other
preparations. The results showed that the two groups treated
with Chinese herbs did significantly better than the placebo
group, as measured both by the patients’ subjective
reports and by their gastroenterologists’ evaluation.
The authors of the study commented that, to their knowledge,
“this is the first clinical trial in Chinese herbal
medicine that fully adheres to the traditional Chinese diagnostic
and treatment processes while using a strict and accepted
methodological protocol.”
The third study—of treatments for pain due to HIV-related
peripheral neuropathy—was more significant for the research
issues it underlined than for its results. The study compared
treatment with acupuncture against Amitriptyline (a conventional
medical medication) and found that neither was effective.
The authors of this study acknowledged that this result was
very likely due to a problem with the study’s design.
Such design problems occur frequently when Chinese medicine
is studied within a western research protocol, because the
nature of Chinese medical treatment—based on individual
characteristics—is not easily standardized, or generalizable
over a broad range of cases as is required by western research
methods. In addition, the creation of a meaningful placebo
has also posed a hurdle for accurate research. Because while
it is easy to put a neutral substance into a capsule, it is
hard to give someone truly “neutral” acupuncture,
or to fool them into thinking they haven’t had any acupuncture
at all. Without a credible placebo, it is difficult for researchers
to distinguish between the effects of “mind over matter”
and the effects of the procedure itself.
In the context of these obstacles, this issue of JAMA is
all the more significant because it takes conventional research
past the point of rejecting alternative therapies on the basis
of failure to show benefit in poorly designed studies. If
research design challenges continue to be acknowledged by
western researchers, they may ultimately spark better studies,
with more accurate evaluation of this medical system that
has already stood the test of time.
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